Immunity to fungal infections

被引:484
作者
Romani, L [1 ]
机构
[1] Univ Perugia, Microbiol Sect, Dept Expt Med & Biochem Sci, I-06122 Perugia, Italy
关键词
D O I
10.1038/nri1255
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The topic of immunity to fungal infections is of interest to a wide range of disciplines, from microbiology to immunology. It is of particular interest in terms of therapy of HIV-infected individuals, and patients with cancer or individuals who have received transplants. Understanding the nature and function of the immune response to fungi is an exciting challenge that might set the stage for new approaches to the treatment of fungal diseases, from immunotherapy to vaccines. The past decade has witnessed the development of a wide range of new approaches to elucidate events that occur at the host-fungus interface.
引用
收藏
页码:11 / 23
页数:13
相关论文
共 132 条
  • [1] Mammalian Toll-like receptors
    Akira, S
    [J]. CURRENT OPINION IN IMMUNOLOGY, 2003, 15 (01) : 5 - 11
  • [2] PRODUCTION AND FUNCTION OF CYTOKINES IN NATURAL AND ACQUIRED-IMMUNITY TO CANDIDA-ALBICANS INFECTION
    ASHMAN, RB
    PAPADIMITRIOU, JM
    [J]. MICROBIOLOGICAL REVIEWS, 1995, 59 (04) : 646 - &
  • [3] Relation between recurrent vulvovaginal candidiasis, vaginal concentrations of mannose-binding lectin, and a mannose-binding lectin gene polymorphism in latvian women
    Babula, O
    Lazdane, G
    Kroica, J
    Ledger, WJ
    Witkin, SS
    [J]. CLINICAL INFECTIOUS DISEASES, 2003, 37 (05) : 733 - 737
  • [4] Dendritic cells in the induction of protective and nonprotective anticryptococcal cell-mediated immune responses
    Bauman, SK
    Nichols, KL
    Murphy, JW
    [J]. JOURNAL OF IMMUNOLOGY, 2000, 165 (01) : 158 - 167
  • [5] BELLOCCHIO S, IN PRESS J IMMUNOL
  • [6] QUANTITATIVE RELATIONSHIPS BETWEEN CIRCULATING LEUKOCYTES AND INFECTION IN PATIENTS WITH ACUTE LEUKEMIA
    BODEY, GP
    BUCKLEY, M
    SATHE, YS
    FREIREICH, EJ
    [J]. ANNALS OF INTERNAL MEDICINE, 1966, 64 (02) : 328 - +
  • [7] A dendritic cell vaccine against invasive aspergillosis in allogeneic hematopoietic transplantation
    Bozza, S
    Perruccio, K
    Montagnoli, C
    Gaziano, R
    Bellocchio, S
    Burchielli, E
    Nkwanyuo, G
    Pitzurra, L
    Velardi, A
    Romani, L
    [J]. BLOOD, 2003, 102 (10) : 3807 - 3814
  • [8] Dendritic cells transport conidia and hyphae of Aspergillus fumigatus from the airways to the draining lymph nodes and initiate disparate Th responses to the fungus
    Bozza, S
    Gaziano, R
    Spreca, A
    Bacci, A
    Montagnoli, C
    di Francesco, P
    Romani, L
    [J]. JOURNAL OF IMMUNOLOGY, 2002, 168 (03) : 1362 - 1371
  • [9] Brandhorst TT, 1999, J EXP MED, V189, P1207, DOI 10.1084/jem.189.8.1207
  • [10] Interplay between protective and inhibitory antibodies dictates the outcome of experimentally disseminated candidiasis in recipients of a Candida albicans vaccine
    Bromuro, C
    Torosantucci, A
    Chiani, P
    Conti, S
    Polonelli, L
    Cassone, A
    [J]. INFECTION AND IMMUNITY, 2002, 70 (10) : 5462 - 5470