Isolation of a 2-pyrone compound as an antioxidant from a fungus and its new reaction product with 1,1-diphenyl-2-picrylhydrazyl radical

被引：24

作者：

Hirota, A ^{[1
]}

Nemoto, A ^{[1
]}

Tsuchiya, Y ^{[1
]}

Hojo, H ^{[1
]}

Abe, N ^{[1
]}

机构：

[1] Univ Shizuoka, Sch Food & Nutr Sci, Appl Microbiol Lab, Shizuoka 4228526, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 1999年 / 63卷 / 02期

关键词：

indophenol-reducing compound; antioxidant; radical-scavenging activity;

D O I：

10.1271/bbb.63.418

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The indophenol-reducing compound, 4-hydroxy-3,6-dimethyl-2 H-pyrane-2-one (I), was isolated from the culture filtrate of an unidentified fungus. I also reacted with the DPPH radical to form a reaction product IV which was determined to be 1-[4-(3,4-dihydro-3,6-dimethyl-2,4-dioxo- 2 H-pyran-3-yl)phenyl]-1-phenyl-2-picrylhydrazine. This is the first report describing the formation of an adduct of the DPPH radical and its scavenger.

引用

页码：418 / 420

页数：3

共 9 条

[1] Novel DPPH radical scavengers, bisorbicillinol and demethyltrichodimerol, from a fungus [J].

Abe, N ;

Murata, T ;

Hirota, A .

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 1998, 62 (04) :661-666

[2]

BLOIS MS, 1958, NATURE, V181, P1188

[3] ISOLATION + STRUCTURE OF METHYLTRIACETIC LACTONE FROM PENICILLIUM STIPITATUM [J].

BRENNEISEN, PE ;

ACKER, TE ;

TANENBAUM, SW .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1964, 86 (06) :1264-&

[4] New antioxidative indophenol-reducing phenol compounds isolated from the Mortierella sp. fungus [J].

Hirota, A ;

Morimitsu, Y ;

Hojo, H .

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 1997, 61 (04) :647-650

[5] NEW INDOPHENOL-REDUCING 1,3-DICARBONYL COMPOUND FROM STREPTOMYCES [J].

HIROTA, A ;

HIRATA, M ;

MORIMITSU, Y ;

HIROTA, H .

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 1994, 58 (04) :792-793

[6] Two oxazolyl compounds and a monosubstituted alpha-pyrone as free-radical scavengers isolated from a fungus [J].

Morimitsu, Y ;

Hirota, A .

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 1997, 61 (09) :1428-1433

[7] Ansamycin antibiotics as free radical scavengers isolated from Streptomyces by using the bactericidal action of the hydroxyl radical [J].

Morimitsu, Y ;

Hirota, A .

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 1996, 60 (09) :1507-1509

[8] NMR analytical approach to clarify the antioxidative molecular mechanism of catechins using 1,1-diphenyl-2-picrylhydrazyl [J].

Sawai, Y ;

Sakata, K .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1998, 46 (01) :111-114

[9]

YOSHIDA T, 1989, CHEM PHARM BULL, V37, P1919

← 1 →