How is the mouse germ-cell lineage established?

被引：68

作者：

McLaren, A

Lawson, KA

机构：

[1] Wellcome Trust Canc Res UK, Gurdon Inst, Cambridge CB2 1QR, England

[2] Western Gen Hosp, MRC, Human Genet Unit, Edinburgh EH4 2XU, Midlothian, Scotland

来源：

DIFFERENTIATION | 2005年 / 73卷 / 9-10期

基金：

英国惠康基金;

关键词：

mouse primordial germ cells; gastrulation;

D O I：

10.1111/j.1432-0436.2005.00049.x

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Six cells have been detected in the early mouse embryo that express the transcriptional repressor Blimp1-as also do all the 40 or so cells that constitute the founder germ cell pool a day later. Are these half-dozen cells the ancestors of the entire mouse germ cell lineage?

引用

收藏

页码：435 / 437

页数：3

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