Apolipoprotein E as a risk factor for coronary heart disease: A genetic and molecular biology approach

被引：53

作者：

deKnijff, P

Havekes, LM

机构：

[1] TNO PG,GAUBIUS LAB,LEIDEN,NETHERLANDS

[2] LEIDEN UNIV,MGC DEPT HUMAN GENET,SYLVIUS LAB,2300 RA LEIDEN,NETHERLANDS

来源：

CURRENT OPINION IN LIPIDOLOGY | 1996年 / 7卷 / 02期

关键词：

D O I：

10.1097/00041433-199604000-00002

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

For a long time it has been suggested that apolipoprotein E(4) is a major risk factor for coronary heart disease although indisputable proof has been lacking. However, context-dependent influences of apolipoprotein E polymorphism on the risk for coronary heart disease have been reported; that is, depending on ethnic origin, gender and lifestyle, apolipoprotein E(4) confers a major risk factor for coronary heart disease.

引用

页码：59 / 63

页数：5

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