Preparation and determination of X-ray-crystal and NMR-solution structures of γ2,3,4-peptides

被引：103

作者：

Seebach, D ^{[1
]}

Brenner, M ^{[1
]}

Rueping, M ^{[1
]}

Schweizer, B ^{[1
]}

Jaun, B ^{[1
]}

机构：

[1] ETH Zentrum, Organ Chem Lab, CH-8092 Zurich, Switzerland

来源：

CHEMICAL COMMUNICATIONS | 2001年 / 02期

关键词：

D O I：

10.1039/b008377l

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(R,R,R)-gamma -Amino acids with side chains in the 2-, 3-, and 4-positions, prepared by addition of acyloxazolidinones toa nitroolefin and hydrogenation, have been coupled to gamma -tetra-, and gamma -hexapeptides which are shown to form (M)-2.6(14) helices in the crystal state and in MeOH solution.

引用

页码：207 / 208

页数：2

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