Effect of maternal antibodies on the infant immune response

被引：96

作者：

Glezen, WP ^{[1
]}

机构：

[1] Baylor Coll Med, Dept Mol Virol & Microbiol, Houston, TX 77030 USA

来源：

VACCINE | 2003年 / 21卷 / 24期

关键词：

maternal antibodies; infant immunity; vaccine response;

D O I：

10.1016/S0264-410X(03)00339-6

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Transplacentally-acquired antibodies are important for protection of infants in the early months of life. Maternal antibodies may dampen the infant's primary antibody response to infection or immunization. Even without a measurable response to the initial antigen exposure, the infant will usually have evidence of priming at the time of repeat exposure. No evidence for the development of fetal tolerance after immunization during pregnancy has occurred subsequently in infants following active vaccination. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：3389 / 3392

页数：4

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