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Bilateral subthalamic nucleus stimulation improves health-related quality of life in Parkinsonian patients

被引：52
作者：
Erola, T
Karinen, P
Heikkinen, E
Tuominen, J
Haapaniemi, T
Koivukangas, J
Myllylä, V
机构：
[1] Oulu Univ Hosp, Dept Neurosurg, FIN-90029 Oys, Finland
[2] Oulu Univ Hosp, Dept Neurol, Oys, Finland
来源：
PARKINSONISM & RELATED DISORDERS | 2005年 / 11卷 / 02期
关键词：
Parkinson's disease; health-related quality of life; deep brain stimulation; subthalamic nucleus; Parkinson's disease questionnaire; Nottingham health profile;
D O I：
10.1016/j.parkreldis.2004.08.006
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Parkinson's disease (PD) is a common neurological disorder. Recently, bilateral deep brain stimulation (DBS) of the subthalamic nucleus (STN) has become an option in the treatment of severe PD. We measured the health-related quality of life (HRQoL) of 27 parkinsonian patients, who underwent a bilateral STN-operation. The instruments used for the evaluation of the HRQoL were the Parkinson's Disease Questionnaire (PDQ-39) and the Finnish version of the Nottingham Health Profile (NHP). We found that the quality of life significantly improved when measured with both HRQoL scales. Clinical improvement and improvement in HRQoL were positively correlated. (c) 2004 Elsevier Ltd. All rights reserved.
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页码：89 / 94
页数：6
相关论文
共 26 条
[1]   Effects of bilateral subthalamic stimulation on cognitive function in Parkinson disease [J].
Alegret, M ;
Junqué, C ;
Valldeoriola, F ;
Vendrell, P ;
Pilleri, M ;
Rumià, J ;
Tolosa, E .
ARCHIVES OF NEUROLOGY, 2001, 58 (08) :1223-1227
[2]  
Ardouin C, 1999, ANN NEUROL, V46, P217, DOI 10.1002/1531-8249(199908)46:2<217::AID-ANA11>3.0.CO
[3]  
2-Z
[4]  
Benabid AL, 2000, NEUROLOGY, V55, pS40
[5]   Quality of life and parkinson's disease: Translation and validation of the US Parkinson's Disease Questionnaire (PDQ-39) [J].
Bushnell, DM ;
Martin, ML .
QUALITY OF LIFE RESEARCH, 1999, 8 (04) :345-350
[6]   Predictors of effective bilateral subthalamic nucleus stimulation for PD [J].
Charles, PD ;
Van Blercom, N ;
Krack, P ;
Lee, SL ;
Xie, J ;
Besson, G ;
Benabid, AL ;
Pollak, P .
NEUROLOGY, 2002, 59 (06) :932-934
[7]   Health-related quality of life in Parkinson's disease: A study of outpatient clinic attenders [J].
Fitzpatrick, R ;
Peto, V ;
Jenkinson, C ;
Greenhall, R ;
Hyman, N .
MOVEMENT DISORDERS, 1997, 12 (06) :916-922
[8]  
Hagell P, 2000, MOVEMENT DISORD, V15, P224, DOI 10.1002/1531-8257(200003)15:2<224::AID-MDS1004>3.0.CO
[9]  
2-W
[10]   Gender differences in disability and health-related quality of life in patients with Parkinson's disease treated with stereotactic surgery [J].
Hariz, GM ;
Lindberg, M ;
Hariz, MI ;
Bergenheim, AT .
ACTA NEUROLOGICA SCANDINAVICA, 2003, 108 (01) :28-37
123