共 12 条
- [11] SYVANEN AC, 1993, AM J HUM GENET, V52, P46
- [12] Weir BS, 1997, J FORENSIC SCI, V42, P213
An assessment of the utility of single nucleotide polymorphisms (SNPs) for forensic purposes
被引：151
作者：
Gill, P
[1
]
机构：
[1] Forens Sci Serv Inc, Trident Court, Birmingham B37 7YN, W Midlands, England
关键词：
SNP;
polymorphisms;
arrays;
multiplexes;
simulation;
biochips;
D O I：
10.1007/s004149900117
中图分类号：
DF [法律];
D9 [法律];
R [医药、卫生];
学科分类号：
0301 ;
10 ;
摘要：
This paper assesses the use of single nucleotide polymorphisms (SNPs) for forensic analysis. It demonstrates that relatively small arrays of approx. 50 loci are comparable to existing short tandem repeat (STR) multiplexes. A quantitative test, however, is a prerequisite for mixture interpretation. In addition, as the mixture proportion becomes low, it will be necessary to distinguish between the allele and background. Relatively small biallelic arrays are also suitable to distinguish between closely related individuals such as brothers.
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页码：204 / 210
页数：7
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