Linking gene regulation to mRNA production and export

被引：95

作者：

Rodriguez-Navarro, Susana ^{[1
]}

Hurt, Ed ^{[2
]}

机构：

[1] Ctr Invest Principe Felipe, Valencia, Spain

[2] Heidelberg Univ, Zentrum Biochem, Heidelberg, Germany

来源：

CURRENT OPINION IN CELL BIOLOGY | 2011年 / 23卷 / 03期

关键词：

UBIQUITIN-ASSOCIATED DOMAIN; NUCLEAR-PORE; TRANSCRIPTION ELONGATION; COUPLING TRANSCRIPTION; FUNCTIONAL COMPONENT; NUCLEOPORIN NUP214; MRNP DYNAMICS; BUDDING YEAST; THO COMPLEX; SAGA;

D O I：

10.1016/j.ceb.2010.12.002

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Regulation of gene expression can occur at many different levels. One important step in the gene expression process is the transport of mRNA from the nucleus to the cytoplasm. In recent years, studies have described how nuclear mRNA export depends on the steps preceding and following transport through nuclear pore complexes. These include gene activation, transcription, mRNA processing and mRNP assembly and disassembly. In this review, we summarise recent insights into the links between these steps in the gene expression cascade.

引用

收藏

页码：302 / 309

页数：8

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