Transcranial Magnetic Stimulation and Aphasia Rehabilitation

被引:65
作者
Naeser, Margaret A. [1 ]
Martin, Paula I. [1 ]
Ho, Michael [1 ]
Treglia, Ethan [1 ]
Kaplan, Elina [1 ]
Bashir, Shahid [2 ,3 ]
Pascual-Leone, Alvaro [2 ,3 ,4 ]
机构
[1] Boston Univ, Sch Med, Harold Goodglass Boston Univ, Aphasia Res Ctr,Dept Neurol, Boston, MA 02118 USA
[2] Harvard Univ, Sch Med, Berenson Allen Ctr Noninvas Brain Stimulat, Dept Neurol, Boston, MA USA
[3] Beth Israel Deaconess Med Ctr, Boston, MA 02215 USA
[4] Univ Autonoma Barcelona, Inst Guttman Neurorehabil, Inst Univ, Badalona, Spain
来源
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION | 2012年 / 93卷 / 01期
基金
美国国家卫生研究院;
关键词
Aphasia; Rehabilitation; Stroke; Transcranial magnetic stimulation; HUMAN MOTOR CORTEX; PARADOXICAL FUNCTIONAL FACILITATION; INFERIOR PREFRONTAL CORTEX; NONFLUENT APHASIA; POSTSTROKE APHASIA; IMPROVED LANGUAGE; RIGHT-HEMISPHERE; PARS TRIANGULARIS; BRAIN PLASTICITY; PREMOTOR CORTEX;
D O I
10.1016/j.apmr.2011.04.026
中图分类号
R49 [康复医学];
学科分类号
100232 [康复医学];
摘要
Repetitive transcranial magnetic stimulation (rTMS) has been reported to improve naming in chronic stroke patients with nonfluent aphasia since 2005. In part 1, we review the rationale for applying slow, 1-Hz, rTMS to the undamaged right hemisphere in chronic nonfluent aphasia patients after a left hemisphere stroke; and we present a transcranial magnetic stimulation (TMS) protocol used with these patients that is associated with long-term, improved naming post-TMS. In part 2, we present results from a case study with chronic nonfluent aphasia where TMS treatments were followed immediately by speech therapy (constraint-induced language therapy). In part 3, some possible mechanisms associated with improvement after a series of TMS treatments in stroke patients with aphasia are discussed.
引用
收藏
页码:S26 / S34
页数:9
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