Folic acid-conjugated nanostructured materials designed for cancer cell targeting

被引：172

作者：

Pan, D ^{[1
]}

Turner, JL ^{[1
]}

Wooley, KL ^{[1
]}

机构：

[1] Washington Univ, Dept Chem, St Louis, MO 63130 USA

来源：

CHEMICAL COMMUNICATIONS | 2003年 / 19期

关键词：

D O I：

10.1039/b307878g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Shell cross-linked nanoparticles (SCKs) constitute a unique class of materials with amphiphilic core-shell morphology; SCKs are characterised by their structural integrity and available functionality to attach receptor-recognising or receptor-specific ligands on the shell surface and, therefore, hold great potential in drug delivery applications; in an attempt to develop novel, cancer cell specific delivery vehicles, folate receptor targeted SCKs have been prepared.

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页码：2400 / 2401

页数：2

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