JenPep: A novel computational information resource for immunobiology and vaccinology

被引：47

作者：

McSparron, H ^{[1
]}

Blythe, MJ ^{[1
]}

Zygouri, C ^{[1
]}

Doytchinova, IA ^{[1
]}

Flower, DR ^{[1
]}

机构：

[1] Edward Jenner Inst Vaccine Res, Compton RG20 7NN, Berks, England

来源：

JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES | 2003年 / 43卷 / 04期

关键词：

D O I：

10.1021/ci030461e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

JenPep is a relational database containing a compendium of thermodynamic binding data for the interaction of peptides with a range of important immunological molecules: the major histocompatibility complex, TAP transporter, and T cell receptor. The database also includes annotated lists of B cell and T cell epitopes. Version 2.0 of the database is implemented in a bespoke postgreSQL database system and is fully searchable online via a perl/HTML interface (URL: http://www.jenner.ac.uk/JenPep).

引用

页码：1276 / 1287

页数：12

共 70 条

[1] Gapped BLAST and PSI-BLAST: a new generation of protein database search programs [J].

Altschul, SF ;

Madden, TL ;

Schaffer, AA ;

Zhang, JH ;

Zhang, Z ;

Miller, W ;

Lipman, DJ .

NUCLEIC ACIDS RESEARCH, 1997, 25 (17) :3389-3402

[2] A structure-based algorithm to predict potential binding peptides to MHC molecules with hydrophobic binding pockets [J].

Altuvia, Y ;

Sette, A ;

Sidney, J ;

Southwood, S ;

Margalit, H .

HUMAN IMMUNOLOGY, 1997, 58 (01) :1-11

[3] A response calculus for immobilized T cell receptor ligands [J].

Andersen, PS ;

Menné, C ;

Mariuzza, RA ;

Geisler, C ;

Karjalainen, K .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (52) :49125-49132

[4] The InterPro database, an integrated documentation resource for protein families, domains and functional sites [J].

Apweiler, R ;

Attwood, TK ;

Bairoch, A ;

Bateman, A ;

Birney, E ;

Biswas, M ;

Bucher, P ;

Cerutti, T ;

Corpet, F ;

Croning, MDR ;

Durbin, R ;

Falquet, L ;

Fleischmann, W ;

Gouzy, J ;

Hermjakob, H ;

Hulo, N ;

Jonassen, I ;

Kahn, D ;

Kanapin, A ;

Karavidopoulou, Y ;

Lopez, R ;

Marx, B ;

Mulder, NJ ;

Oinn, TM ;

Pagni, M ;

Servant, F ;

Sigrist, CJA ;

Zdobnov, EM .

NUCLEIC ACIDS RESEARCH, 2001, 29 (01) :37-40

[5] PRINTS and PRINTS-S shed light on protein ancestry [J].

Attwood, TK ;

Blythe, MJ ;

Flower, DR ;

Gaulton, A ;

Mabey, JE ;

Maudling, N ;

McGregor, L ;

Mitchell, AL ;

Moulton, G ;

Paine, K ;

Scordis, P .

NUCLEIC ACIDS RESEARCH, 2002, 30 (01) :239-241

[6] BIND - a data specification for storing and describing biomolecular interactions, molecular complexes and pathways [J].

Bader, GD ;

Hogue, CWV .

BIOINFORMATICS, 2000, 16 (05) :465-477

[7]

BHASIN M, 2002, NUCL ACIDS RES

[8] JenPep: a database of quantitative functional peptide data for immunology [J].

Blythe, MJ ;

Doytchinova, IA ;

Flower, DR .

BIOINFORMATICS, 2002, 18 (03) :434-439

[9] Prediction of MHC class II-binding peptides using an evolutionary algorithm and artificial neural network [J].

Brusic, V ;

Rudy, G ;

Honeyman, M ;

Hammer, J ;

Harrison, L .

BIOINFORMATICS, 1998, 14 (02) :121-130

[10] MHCPEP, a database of MHC-binding peptides: update 1997 [J].

Brusic, V ;

Rudy, G ;

Harrison, LC .

NUCLEIC ACIDS RESEARCH, 1998, 26 (01) :368-371

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