The problem of plain vanilla peptides

被引:16
作者
Davis, MM [1 ]
机构
[1] Stanford Univ, Howard Hughes Med Inst, Sch Med, Stanford, CA 94305 USA
[2] Stanford Univ, Dept Microbiol & Immunol, Sch Med, Stanford, CA 94305 USA
关键词
D O I
10.1038/ni0703-649
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The anti-influenza CD8(+) T cell response in HLA-A2 adults is dominated by a specific TCR. The crystal structure of the TCR and peptide-MHC complex show unusual interactions that help to explain the molecular basis of this dominant TCR selection.
引用
收藏
页码:649 / 650
页数:2
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