Suppression of hydroxyl radical formation and protection of nigral neurons by l-deprenyl (selegiline)

被引：37

作者：

Wu, RM ^{[1
]}

Murphy, DL ^{[1
]}

Chiueh, CC ^{[1
]}

机构：

[1] NATL TAIWAN UNIV HOSP, COLL MED, DEPT NEUROL, TAIPEI 10016, TAIWAN

来源：

PHARMACOLOGICAL INTERVENTION IN AGING AND AGE-ASSOCIATED DISORDERS: PROCEEDINGS OF THE SIXTH CONGRESS OF THE INTERNATIONAL ASSOCIATION OF BIOMEDICAL GERONTOLOGY | 1996年 / 786卷

关键词：

D O I：

10.1111/j.1749-6632.1996.tb39078.x

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

引用

页码：379 / 390

页数：12

共 39 条

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[5] HYDROXYL FREE-RADICAL (.OH) FORMATION REFLECTED BY SALICYLATE HYDROXYLATION AND NEUROMELANIN - IN-VIVO MARKERS FOR OXIDANT INJURY OF NIGRAL NEURONS
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[6] CHIUEH CC, 1993, ADV NEUROL, V60, P251
[7] INTRACRANIAL MICRODIALYSIS OF SALICYLIC-ACID TO DETECT HYDROXYL RADICAL GENERATION THROUGH DOPAMINE AUTOOXIDATION IN THE CAUDATE-NUCLEUS - EFFECTS OF MPP
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[J]. FREE RADICAL BIOLOGY AND MEDICINE, 1992, 13 (05) : 581 - 583
[8] ENHANCED HYDROXYL RADICAL GENERATION BY 2'-METHYL ANALOG OF MPTP - SUPPRESSION BY CLORGYLINE AND DEPRENYL
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[J]. SYNAPSE, 1992, 11 (04) : 346 - 348
[9] CHIUEH CC, 1994, J NEURAL TRANSM-SUPP, P189
[10] DEPRENYL SUPPRESSES THE OXIDANT STRESS ASSOCIATED WITH INCREASED DOPAMINE TURNOVER
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