Simple Neurite Tracer: open source software for reconstruction, visualization and analysis of neuronal processes

被引:700
作者
Longair, Mark H. [1 ]
Baker, Dean A. [2 ]
Armstrong, J. Douglas [3 ]
机构
[1] Uni ETH Zurich, Inst Neuroinformat, CH-8057 Zurich, Switzerland
[2] Univ Cambridge, Dept Genet, Cambridge CB2 3EH, England
[3] Univ Edinburgh, Inst Adapt & Neural Computat, Sch Informat, Edinburgh EH8 9AB, Midlothian, Scotland
基金
英国工程与自然科学研究理事会; 英国生物技术与生命科学研究理事会;
关键词
TOOL;
D O I
10.1093/bioinformatics/btr390
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Motivation: Advances in techniques to sparsely label neurons unlock the potential to reconstruct connectivity from 3D image stacks acquired by light microscopy. We present an application for semiautomated tracing of neurons to quickly annotate noisy datasets and construct complex neuronal topologies, which we call the Simple Neurite Tracer.
引用
收藏
页码:2453 / 2454
页数:2
相关论文
共 10 条
[1]  
Frangi AF, 1998, LECT NOTES COMPUT SC, V1496, P130, DOI 10.1007/BFb0056195
[2]   A FORMAL BASIS FOR HEURISTIC DETERMINATION OF MINIMUM COST PATHS [J].
HART, PE ;
NILSSON, NJ ;
RAPHAEL, B .
IEEE TRANSACTIONS ON SYSTEMS SCIENCE AND CYBERNETICS, 1968, SSC4 (02) :100-+
[3]   Metadata matters: access to image data in the real world [J].
Linkert, Melissa ;
Rueden, Curtis T. ;
Allan, Chris ;
Burel, Jean-Marie ;
Moore, Will ;
Patterson, Andrew ;
Loranger, Brian ;
Moore, Josh ;
Neves, Carlos ;
MacDonald, Donald ;
Tarkowska, Aleksandra ;
Sticco, Caitlin ;
Hill, Emma ;
Rossner, Mike ;
Eliceiri, Kevin W. ;
Swedlow, Jason R. .
JOURNAL OF CELL BIOLOGY, 2010, 189 (05) :777-782
[4]   Design and validation of a tool for neurite tracing and analysis in fluorescence microscopy images [J].
Meijering, E ;
Jacob, M ;
Sarria, JCF ;
Steiner, P ;
Hirling, H ;
Unser, M .
CYTOMETRY PART A, 2004, 58A (02) :167-176
[5]   Neuron Tracing in Perspective [J].
Meijering, Erik .
CYTOMETRY PART A, 2010, 77A (07) :693-704
[6]  
Sato Y, 1998, Med Image Anal, V2, P143, DOI 10.1016/S1361-8415(98)80009-1
[7]   A high-level 3D visualization API for Java']Java and ImageJ [J].
Schmid, Benjamin ;
Schindelin, Johannes ;
Cardona, Albert ;
Longair, Martin ;
Heisenberg, Martin .
BMC BIOINFORMATICS, 2010, 11
[8]   L-Measure: a web-accessible tool for the analysis, comparison and search of digital reconstructions of neuronal morphologies [J].
Scorcioni, Ruggero ;
Polavaram, Sridevi ;
Ascoli, Giorgio A. .
NATURE PROTOCOLS, 2008, 3 (05) :866-876
[9]  
SHOLL DA, 1953, J ANAT, V87, P387
[10]  
WINK O, 2000, ICPR 00, V3, P998