A Case Of Convergence: Why Did a Simple Alternative to Canonical Antibodies Arise in Sharks and Camels?

被引：134

作者：

Flajnik, Martin F. ^{[1
]}

Deschacht, Nick ^{[2
,3
]}

Muyldermans, Serge ^{[2
,3
]}

机构：

[1] Univ Maryland, Dept Microbiol & Immunol, Baltimore, MD 21201 USA

[2] Vrije Univ Brussel, Lab Cellular & Mol Immunol, Brussels, Belgium

[3] VIB, Dept Mol & Cellular Interact, Brussels, Belgium

来源：

PLOS BIOLOGY | 2011年 / 9卷 / 08期

关键词：

HEAVY-CHAIN ANTIBODIES; CRYSTAL-STRUCTURE; ANTIGEN-BINDING; LIGHT-CHAINS; NURSE SHARK; DOMAIN; IMMUNOGLOBULINS; RECOGNITION; REPERTOIRE; MATURATION;

D O I：

10.1371/journal.pbio.1001120

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

[No abstract available]

引用

页数：5

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