Using Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry To Detect Carbapenem Resistance within 1 to 2.5 Hours

被引：259

作者：

Burckhardt, Irene ^{[1
]}

Zimmermann, Stefan ^{[1
]}

机构：

[1] Heidelberg Univ, Dept Infect Dis Microbiol & Hyg, D-69115 Heidelberg, Germany

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2011年 / 49卷 / 09期

关键词：

SPECTRUM BETA-LACTAMASE; PNEUMONIAE; EMERGENCE;

D O I：

10.1128/JCM.00287-11

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

In recent years, the percentage of carbapenem-resistant bacteria has increased at an alarming pace and become a major threat for patient survival. Carbapenemase-induced carbapenem resistance can be confirmed through the detection of carbapenem degradation using matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS). This method works for strains carrying NDM-1, VIM-1, VIM-2, KPC-2, and different IMP enzymes.

引用

页码：3321 / 3324

页数：4

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