Evidence and research in rectal cancer

被引：81

作者：

Vatentini, Vincenzo ^{[1
]}

Beets-Tan, Regina ^{[2
]}

Borras, Josep M. ^{[3
]}

Krivokapic, Zoran ^{[4
]}

Leer, Jan Willem ^{[5
]}

Pahlman, Lars ^{[6
]}

Roedel, Claus ^{[7
]}

Schmoll, Hans Joachim ^{[8
]}

Scott, Nigel ^{[9
]}

Van de Velde, Cornelius ^{[10
]}

Verfaillie, Christine ^{[11
]}

机构：

[1] Univ Cattolica Sacro Cuore, Dept Radiat Oncol, I-00168 Rome, Italy

[2] Univ Hosp Maastricht, Dept Radiol, Maastricht, Netherlands

[3] IDIBELL Canc Plan, Dept Hlth, Barcelona, Spain

[4] Clin Ctr Serbia, Inst Digest Dis, Belgrade, Serbia

[5] Radboud Univ Nijmegen, Dept Radiat Oncol, Med Ctr, Nijmegen, Netherlands

[6] Univ Uppsala Hosp, Dept Surg, S-75185 Uppsala, Sweden

[7] Goethe Univ Frankfurt, Dept Radiat Oncol, D-6000 Frankfurt, Germany

[8] Univ Halle Wittenberg, Dept Med Oncol, D-4010 Halle, Germany

[9] St James Univ Hosp, Dept Pathol, Leeds LS9 7TF, W Yorkshire, England

[10] Leiden Univ, Med Ctr, Dept Surg, NL-2300 RA Leiden, Netherlands

[11] ESTRO Off, Brussels, Belgium

来源：

RADIOTHERAPY AND ONCOLOGY | 2008年 / 87卷 / 03期

关键词：

rectal cancer treatment; epidemiology; diagnostic; endorectal ultrasound; computerized tomography; magnetic resonance imaging; pathology; surgery; total mesorectal excision; local excision; combined modality therapy; radiotherapy; pre-operative treatment; post-operative treatment; radiotherapy technique; chemotherapy; concomitant radiochemotherapy; adjuvant chemotherapy; early stage; intermediate stage; advanced stage; local recurrence; acute and late toxicity; quality of life; follow-up; scenario of ongoing research; educational; randomized clinical trial; intraoperative radiotherapy;

D O I：

10.1016/j.radonc.2008.05.022

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The main evidences of epidemiology, diagnostic imaging, pathology, surgery, radiotherapy, chemotherapy and follow-up are reviewed to optimize the routine treatment of rectal cancer according to a multidisciplinary approach. This paper reports on the knowledge shared between different specialists involved in the design and management of the multidisciplinary ESTRO Teaching Course on Rectal Cancer. The scenario of ongoing research is also addressed. In this time of changing treatments, it clearly appears that a common standard for large heterogeneous patient groups have to be substituted by more individualised therapies based on clinical-pathological features and very soon on molecular and genetic markers. Only trained multidisciplinary teams can face this new challenge and tailor the treatments according to the best scientific evidence for each patient. (C) 2008 Elsevier Ireland Ltd. All rights reserved.

引用

页码：449 / 474

页数：26

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