Surface-enhanced Raman detection of nicotinamide in vitamin tablets

被引:42
作者
Pal, T [1 ]
Narayanan, VA [1 ]
Stokes, DL [1 ]
Vo-Dinh, T [1 ]
机构
[1] Oak Ridge Natl Lab, Div Life Sci, Adv Monitoring Dev Grp, Oak Ridge, TN 37831 USA
关键词
Raman; surface-enhanced Raman scattering; nicotinamide; Vitamin B-3;
D O I
10.1016/S0003-2670(98)00192-5
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Nicotinamide is analyzed quantitatively in vitamin tablets using surface-enhanced Raman scattering (SERS) on a silver-coated alumina substrate. Calibration curve of SERS signal intensity versus concentration of nicotinamide was established for quantitative analysis of this compound for detection at parts per million (ppm) level, SERS spectra of related compounds, nicotine, nicotinic acid, isonicotinic acid, and isonicotinamide were also recorded. Salient features of their spectra are compared and discussed. (C) 1998 Elsevier Science B.V.
引用
收藏
页码:21 / 28
页数:8
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