Diagnostic and therapeutic applications of lytic phages

被引：18

作者：

Mandeville, R

Griffiths, M

Goodridge, L

McIntyre, L

Ilenchuk, TT

机构：

[1] Biophage Pharma Inc, Montreal, PQ H4P 2R2, Canada

[2] Univ Guelph, Guelph, ON N1G 2W1, Canada

[3] Univ Wyoming, Dept Anim Sci, Laramie, WY 82071 USA

[4] Massey Univ, N Shore MSC, Inst Food Nutr & Human Hlth, Auckland, New Zealand

来源：

ANALYTICAL LETTERS | 2003年 / 36卷 / 15期

关键词：

lytic phages; phages; diagnosis; therapy; bacteria; reporter genes; luciferase;

D O I：

10.1081/AL-120026569

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The ability of lytic phages to rapidly kill and lyse infected bacteria, the specificity of phages for particular bacteria, and the ability of phages to increase in number during the infection process make phages excellent potential diagnostic and therapeutic agents for fighting bacterial disease. However, temperate phages are of little use in phage diagnostics and therapy.

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页码：3241 / 3259

页数：19

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