Sleep and Cognitive Abnormalities in Acute Minor Thalamic Infarction

被引：57

作者：

Wu, Wei ^{[1
]}

Cui, Linyang ^{[1
]}

Fu, Ying ^{[1
]}

Tian, Qianqian ^{[1
]}

Liu, Lei ^{[1
]}

Zhang, Xuan ^{[1
]}

Du, Ning ^{[1
]}

Chen, Ying ^{[1
]}

Qiu, Zhijun ^{[1
]}

Song, Yijun ^{[1
]}

Shi, Fu-Dong ^{[1
,2
]}

Xue, Rong ^{[1
]}

机构：

[1] Tianjin Med Univ Gen Hosp, Dept Neurol, Tianjin 300052, Peoples R China

[2] St Josephs Hosp, Barrow Neurol Inst, Dept Neurol, Phoenix, AZ 85013 USA

来源：

NEUROSCIENCE BULLETIN | 2016年 / 32卷 / 04期

关键词：

Acute minor thalamic infarction; Polysomnography; Cognition; ISCHEMIC-STROKE; HYPERSOMNIA; LESIONS; IMPAIRMENT; EVOLUTION; MEMORY; EEG;

D O I：

10.1007/s12264-016-0036-7

中图分类号：

Q189 [神经科学];

学科分类号：

071006 [神经生物学];

摘要：

In order to characterize sleep and the cognitive patterns in patients with acute minor thalamic infarction (AMTI), we enrolled 27 patients with AMTI and 12 matched healthy individuals. Questionnaires about sleep and cognition as well as polysomnography (PSG) were performed on days 14 and 90 post-stroke. Compared to healthy controls, in patients with AMTI, hyposomnia was more prevalent; sleep architecture was disrupted as indicated by decreased sleep efficiency, increased sleep latency, and decreased non-rapid eye movement sleep stages 2 and 3; more sleep-related breathing disorders occurred; and cognitive functions were worse, especially memory. While sleep apnea and long-delay memory recovered to a large extent in the patients, other sleep and cognitive function deficit often persisted. Patients with AMTI are at an increased risk for hyposomnia, sleep structure disturbance, sleep apnea, and memory deficits. Although these abnormalities improved over time, the slow and incomplete improvement suggest that early management should be considered in these patients.

引用

页码：341 / 348

页数：8

共 24 条

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Hypersomnia following paramedian thalamic stroke: A report of 12 patients [J].