Plant targets for Pseudomonas syringae type III effectors: virulence targets or guarded decoys?

被引:179
作者
Block, Anna
Alfano, James R. [1 ]
机构
[1] Univ Nebraska, Ctr Plant Sci Innovat, Lincoln, NE 68588 USA
基金
美国国家卫生研究院; 美国国家科学基金会; 美国农业部;
关键词
PATTERN-RECOGNITION RECEPTORS; PROGRAMMED CELL-DEATH; PV. TOMATO DC3000; PROTEIN-TYROSINE-PHOSPHATASE; ARABIDOPSIS INNATE IMMUNITY; SECRETION SYSTEM EFFECTORS; E3 UBIQUITIN LIGASE; DISEASE RESISTANCE; BACTERIAL EFFECTORS; CYSTEINE PROTEASE;
D O I
10.1016/j.mib.2010.12.011
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The phytopathogenic bacterium Pseudomonas syringae can suppress both pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) and effector-triggered immunity (ETI) by the injection of type III effector (T3E) proteins into host cells. T3Es achieve immune suppression using a variety of strategies including interference with immune receptor signaling, blocking RNA pathways and vesicle trafficking, and altering organelle function. T3Es can be recognized indirectly by resistance proteins monitoring specific T3E targets resulting in ETI. It is presently unclear whether the monitored targets represent bona fide virulence targets or guarded decoys. Extensive overlap between PTI and ETI signaling suggests that T3Es may suppress both pathways through common targets and by possessing multiple activities.
引用
收藏
页码:39 / 46
页数:8
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