Plant targets for Pseudomonas syringae type III effectors: virulence targets or guarded decoys?

被引：178

作者：

Block, Anna

Alfano, James R. ^{[1
]}

机构：

[1] Univ Nebraska, Ctr Plant Sci Innovat, Lincoln, NE 68588 USA

来源：

CURRENT OPINION IN MICROBIOLOGY | 2011年 / 14卷 / 01期

基金：

美国国家卫生研究院; 美国农业部; 美国国家科学基金会;

关键词：

PATTERN-RECOGNITION RECEPTORS; PROGRAMMED CELL-DEATH; PV. TOMATO DC3000; PROTEIN-TYROSINE-PHOSPHATASE; ARABIDOPSIS INNATE IMMUNITY; SECRETION SYSTEM EFFECTORS; E3 UBIQUITIN LIGASE; DISEASE RESISTANCE; BACTERIAL EFFECTORS; CYSTEINE PROTEASE;

D O I：

10.1016/j.mib.2010.12.011

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The phytopathogenic bacterium Pseudomonas syringae can suppress both pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) and effector-triggered immunity (ETI) by the injection of type III effector (T3E) proteins into host cells. T3Es achieve immune suppression using a variety of strategies including interference with immune receptor signaling, blocking RNA pathways and vesicle trafficking, and altering organelle function. T3Es can be recognized indirectly by resistance proteins monitoring specific T3E targets resulting in ETI. It is presently unclear whether the monitored targets represent bona fide virulence targets or guarded decoys. Extensive overlap between PTI and ETI signaling suggests that T3Es may suppress both pathways through common targets and by possessing multiple activities.

引用

收藏

页码：39 / 46

页数：8

相关论文

共 72 条

[1] Indirect activation of a plant nucleotide binding site-leucine-rich repeat protein by a bacterial protease [J].

Ade, Jules ;

DeYoung, Brody J. ;

Golstein, Catherine ;

Innes, Roger W. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (07) :2531-2536

[2] MAP kinase signalling cascade in Arabidopsis innate immunity [J].

Asai, T ;

Tena, G ;

Plotnikova, J ;

Willmann, MR ;

Chiu, WL ;

Gomez-Gomez, L ;

Boller, T ;

Ausubel, FM ;

Sheen, J .

NATURE, 2002, 415 (6875) :977-983

[3] Bacterial polysaccharides suppress induced innate immunity by calcium chelation [J].

Aslam, Shazia N. ;

Newman, Mari-Anne ;

Erbs, Gitte ;

Morrissey, Kate L. ;

Chinchilla, Delphine ;

Boller, Thomas ;

Jensen, Tina Tandrup ;

De Castro, Cristina ;

Ierano, Teresa ;

Molinaro, Antonio ;

Jackson, Robert W. ;

Knight, Marc R. ;

Cooper, Richard M. .

CURRENT BIOLOGY, 2008, 18 (14) :1078-1083

[4] Genetic and molecular evidence that the Pseudomonas syringae type III effector protein AvrRpt2 is a cysteine protease [J].

Axtell, MJ ;

Chisholm, ST ;

Dahlbeck, D ;

Staskawicz, BJ .

MOLECULAR MICROBIOLOGY, 2003, 49 (06) :1537-1546

[5] Initiation of RPS2-specified disease resistance in Arabidopsis is coupled to the AvrRpt2-directed elimination of RIN4 [J].

Axtell, MJ ;

Staskawicz, BJ .

CELL, 2003, 112 (03) :369-377

[6] Phytopathogen type III effector weaponry and their plant targets [J].

Block, Anna ;

Li, Guangyong ;

Fu, Zheng Qing ;

Alfano, James R. .

CURRENT OPINION IN PLANT BIOLOGY, 2008, 11 (04) :396-403

[7] The Pseudomonas syringae type III effector HopG1 targets mitochondria, alters plant development and suppresses plant innate immunity [J].

Block, Anna ;

Guo, Ming ;

Li, Guangyong ;

Elowsky, Christian ;

Clemente, Thomas E. ;

Alfano, James R. .

CELLULAR MICROBIOLOGY, 2010, 12 (03) :318-330

[8] TAL effectors: finding plant genes for disease and defense [J].

Bogdanove, Adam J. ;

Schornack, Sebastian ;

Lahaye, Thomas .

CURRENT OPINION IN PLANT BIOLOGY, 2010, 13 (04) :394-401

[9] Innate Immunity in Plants: An Arms Race Between Pattern Recognition Receptors in Plants and Effectors in Microbial Pathogens [J].

Boller, Thomas ;

He, Sheng Yang .

SCIENCE, 2009, 324 (5928) :742-744

[10] A Renaissance of Elicitors: Perception of Microbe-Associated Molecular Patterns and Danger Signals by Pattern-Recognition Receptors [J].

Boller, Thomas ;

Felix, Georg .

ANNUAL REVIEW OF PLANT BIOLOGY, 2009, 60 :379-406

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