The relationship of obesity, age, and carpal tunnel syndrome: More complex than was thought?

被引:90
作者
Bland, JDP [1 ]
机构
[1] Kent & Canterbury Hosp, EEG Dept, Canterbury CT1 3NG, Kent, England
关键词
age; body mass index; carpal tunnel syndrome; obesity; risk factors;
D O I
10.1002/mus.20408
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Previous reports have shown that obesity is a risk factor for carpal tunnel syndrome (CTS). This study was performed to investigate whether this could be confirmed in a large, existing cohort of patients and to explore the interaction between age and body mass index (BMI) as risk factors. Demographic and clinical data were collected from 6096 patients referred to a subregional neurophysiology service for diagnosis of possible CTS. Patients presenting with their second CTS and those with diabetes or thyroid disease were excluded. Subjects in whom nerve conduction studies (NCS) confirmed CTS were compared with those having normal NCS. After exclusions, there were 4166 patients for analysis of whom 11 had incomplete data. A total of 2408 of 4155 proved to have definite neurophysiological evidence of CTS. Of these patients, 1150 were over the age of 63 years. Univariate and multivariate analyses demonstrated that increased BMI is a significant independent risk factor for CTS in patients under the age of 63 years, but is less important in older patients. Patients over the age of 63 years have a different pattern of risk factors for CTS than younger patients. This suggests that CTS in the elderly population may have different underlying pathogenetic mechanisms.
引用
收藏
页码:527 / 532
页数:6
相关论文
共 27 条
[11]   Prevalence and incidence of carpel tunnel syndrome in a meat packing plant [J].
Gorsche, RG ;
Wiley, JP ;
Renger, RF ;
Brant, RF ;
Gemer, TY ;
Sasyniuk, TM .
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 1999, 56 (06) :417-422
[12]   The genetic contribution to carpal tunnel syndrome in women: A twin study [J].
Hakim, AJ ;
Cherkas, L ;
El Zayat, S ;
MacGregor, AJ ;
Spector, TD .
ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH, 2002, 47 (03) :275-279
[13]   Practice parameter: Electrodiagnostic studies in carpal tunnel syndrome - Report of the American Association of Electrodiagnostic Medicine, American Academy of Neurology, and the American Academy of Physical Medicine and Rehabilitation [J].
Jablecki, CK ;
Andary, MT ;
Floeter, MK ;
Miller, RG ;
Quartly, CA ;
Vennix, MJ ;
Wilson, JR .
NEUROLOGY, 2002, 58 (11) :1589-1592
[14]   Evaluation of age, body mass index, and wrist index as risk factors for carpal tunnel syndrome severity [J].
Kouyoumdjian, JA ;
Zanetta, DMT ;
Morita, MPA .
MUSCLE & NERVE, 2002, 25 (01) :93-97
[15]   Association of obesity, gender, age and occupation with carpal tunnel syndrome [J].
Lam, N ;
Thurston, A .
AUSTRALIAN AND NEW ZEALAND JOURNAL OF SURGERY, 1998, 68 (03) :190-193
[16]   COVARIATES OF HUMAN PERIPHERAL-NERVE FUNCTION .1. NERVE-CONDUCTION VELOCITY AND AMPLITUDE [J].
LETZ, R ;
GERR, F .
NEUROTOXICOLOGY AND TERATOLOGY, 1994, 16 (01) :95-104
[17]   Risk factors for carpal tunnel syndrome in a general population [J].
Nordstrom, DL ;
Vierkant, RA ;
DeStefano, F ;
Layde, PM .
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 1997, 54 (10) :734-740
[19]  
Salerno DF, 1998, MUSCLE NERVE, V21, P999, DOI 10.1002/(SICI)1097-4598(199808)21:8<999::AID-MUS3>3.0.CO
[20]  
2-0