Makaluvamine P, a new cytotoxic pyrroloiminoquinone from Zyzzya cf. fuliginosa

被引:42
作者
Casapullo, A
Cutignano, A
Bruno, I
Bifulco, G
Debitus, C
Gomez-Paloma, L
Riccio, R [1 ]
机构
[1] Univ Salerno, Dipartimento Sci Farmaceut, I-84084 Fisciano, SA, Italy
[2] IRD, Ctr Noumea, Noumea 98848, New Caledonia
来源
JOURNAL OF NATURAL PRODUCTS | 2001年 / 64卷 / 10期
关键词
D O I
10.1021/np010053+
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
A new pyrroloiminoquinone alkaloid (1) belonging to the makaluvamine family has been isolated from the sponge Zyzzya cf. fuliginosa collected in the waters off the Vanuatu Islands. The compound, designated makulavamine P, was characterized on the basis of its spectral data and displayed cytoxicity in the muM range on KB cells and antioxidant activity.
引用
收藏
页码:1354 / 1356
页数:3
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