Enhancing the inhibitory effect of nicotinamide upon collagen II induced arthritis in mice using N-acetylcysteine

被引:7
作者
Kröger, H
Hauschild, A
Ohde, M
Bache, K
Voigt, WP
Ehrlich, W
机构
[1] Deutsch Rheumaforschungszentrum Berlin DRIZ, D-10115 Berlin, Germany
[2] Bundesinst Gesundheitlichen Verbraucherschutz & V, D-12277 Berlin, Germany
关键词
D O I
10.1023/A:1020284810976
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
We could show that both nicotinamide and N-acetylcysteine inhibit collagen induced arthritis in mice. In the present paper, using lower doses of each, we applied combinations of these two substances. We were able to confirm potentiating effects of these combinations. These results may allow new perspectives for the therapy of arthritis to emerge.
引用
收藏
页码:111 / 115
页数:5
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