VEGF receptor signal transduction - A brief update

被引：74

作者：

Claesson-Welsh, Lena ^{[1
]}

机构：

[1] Uppsala Univ, Dept Immunol Genet & Pathol, Rudbeck Lab, Dag Hammarskjoldsv 20, S-75185 Uppsala, Sweden

来源：

VASCULAR PHARMACOLOGY | 2016年 / 86卷

关键词：

ENDOTHELIAL-GROWTH-FACTOR; TYROSINE PHOSPHORYLATION SITES; ADAPTER PROTEIN; CELL MIGRATION; BLOOD-VESSELS; KINASE; ACTIVATION; ANGIOGENESIS; FLT-1; MICE;

D O I：

10.1016/j.vph.2016.05.011

中图分类号：

R9 [药学];

学科分类号：

100702 [药剂学];

摘要：

Vascular endothelial growth factor (VEGF) signal transduction through receptor tyrosine lcinases VEGF receptor 1, -2 and -3 is of crucial importance for monocytes/macrophages, blood vascular endothelial and lymphatic endothelial cells both in physiology and in a number of pathologies notably cancer. This brief review summarizes the current status of VEGF receptor signaling with emphasis on in vivo data. (C) 2016 Elsevier Inc All rights reserved.

引用

页码：14 / 17

页数：4

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