Human cellular inflammation in the pathology of acute cerebral ischaemia

被引:55
作者
Price, CJS
Warburton, EA
Menon, DK
机构
[1] Addenbrookes Hosp, Dept Med, Cambridge CB2 2QQ, England
[2] Addenbrookes Hosp, Div Stroke Med, Cambridge CB2 2QQ, England
[3] Univ Cambridge, Cambridge CB2 1TN, England
关键词
D O I
10.1136/jnnp.74.11.1476
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Leucocytes form important effector pathways for inflammation. This article reviews the clinical evidence for the presence of a cellular inflammatory response in cerebral ischaemia, and attempts to define its temporal profile and spatial distribution. The processes involved in recruitment and activation of leucocytes in this context are addressed, and the successes and failures of interventions aimed at these processes discussed.
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收藏
页码:1476 / 1484
页数:9
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