Mechanical Characterization of Porcine Corneas

被引:73
作者
Boschetti, F. [1 ,2 ]
Triacca, V. [3 ]
Spinelli, L. [4 ]
Pandolfi, A. [1 ]
机构
[1] Politecn Milan, Dipartimento Ingn Strutturale, Lab Biol Struct Mech, I-20133 Milan, Italy
[2] IRCCS Ist Ortoped Galeazzi, I-20161 Milan, Italy
[3] Ecole Polytech Fed Lausanne, Inst Bioengn, CH-1015 Lausanne, Switzerland
[4] SKE Srl, I-20161 Milan, Italy
来源
JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME | 2012年 / 134卷 / 03期
关键词
porcine corneas; inflation experiments; uniaxial experiments; viscoelasticity; anisotropy; shell linear theory; BIOMECHANICAL PROPERTIES; BOVINE; ANISOTROPY; MODEL;
D O I
10.1115/1.4006089
中图分类号
Q6 [生物物理学];
学科分类号
071011 [生物物理学];
摘要
An experimental program has been carried out in order to investigate the mechanical behavior of porcine corneas. We report the results of inflation tests on the whole cornea and uniaxial tests on excised corneal strips, performed on 51 fresh porcine eyes. Uniaxial tests have been performed on specimens cut from previously inflated corneas. The cornea behavior is characterized by means of elastic stiffness, measured on both average pressure-apex displacement and average uniaxial stress-strain curves; and by means of transversal contraction coefficient, peak stress, and failure stress measured on uniaxial stress-strain curves. Uniaxial tests performed on excised strips allowed to measure the anisotropy in the corneal stiffness and to compare the stiffness of the cornea with the one of the sclera. Viscous properties of the cornea have been obtained through uniaxial relaxation curves on excised corneal strips. The relevant geometrical parameters have been measured and, with the aid of the elastic thin shell theory, a stress-strain curve has been derived from the average inflation test data and compared with similar data available in the literature. The experimental system has been developed in view of future applications to the mechanical testing of both porcine and human corneas. [DOI: 10.1115/1.4006089]
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页数:9
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