Finding Effective Treatments for COVID-19 Scientific Integrity and Public Confidence in a Time of Crisis

被引：43

作者：

Goodman, Jesse L. ^{[1
]}

Borio, Luciana ^{[2
]}

机构：

[1] Georgetown Univ, 3900 Reservoir Rd, Washington, DC 20057 USA

[2] In Q Tel, Arlington, VA USA

来源：

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION | 2020年 / 323卷 / 19期

关键词：

D O I：

10.1001/jama.2020.6434

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

This Viewpoint discusses the risks to patients and public health posed by the FDA's politically pressured Emergency Use Authorization (EUA) of chloroquine and hydroxychloroquine for COVID-19 treatment, and proposes principles to follow to ensure new therapies are studied properly and quickly to maximize benefits and minimize risks to patients.

引用

页码：1899 / 1900

页数：2

共 10 条

[1]

[Anonymous], 2020, COMMUNICATION 0406

[2]

Diamond Dan., 2020, POLITICO

[3]

Fuerstein A, 2020, STAT

[4]

Studying "Secret Serums" - Toward Safe, Effective Ebola Treatments [J].

Goodman, Jesse L. .

NEW ENGLAND JOURNAL OF MEDICINE, 2014, 371 (12) :1086-1089

[5]

Treating COVID-19-Off-Label Drug Use, Compassionate Use, and Randomized Clinical Trials During Pandemics [J].

Kalil, Andre C. .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2020, 323 (19) :1897-1898

[6]

Ethics of randomized trials in a public health emergency [J].

London, Alex John ;

Omotade, Olayemi O. ;

Mello, Michelle M. ;

Keusch, Gerald T. .

PLOS NEGLECTED TROPICAL DISEASES, 2018, 12 (05)

[7]

Of chloroquine and COVID-19 [J].

Touret, Franck ;

de lamballerie, Xavier .

ANTIVIRAL RESEARCH, 2020, 177

[8]

U.S. Department of Health and Human Services, 2017, EM US AUTH MED PROD

[9]

US Food and Drug Administration, 2020, REQ EM US AUTH US CH

[10]

Clinical trial analysis of 2019-nCoV therapy registered in China [J].

Zhang, Qi ;

Wang, Yakun ;

Qi, Changsong ;

Shen, Lin ;

Li, Jian .

JOURNAL OF MEDICAL VIROLOGY, 2020, 92 (06) :540-545

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