Multiple γc-dependent cytokines regulate T-cell development

被引：57

作者：

Malek, TR ^{[1
]}

Porter, BO

He, YW

机构：

[1] Univ Miami, Sch Med, Dept Microbiol & Immunol, Miami, FL 33136 USA

[2] Univ Washington, Sch Med, Dept Immunol, Seattle, WA 98195 USA

来源：

IMMUNOLOGY TODAY | 1999年 / 20卷 / 02期

关键词：

D O I：

10.1016/S0167-5699(98)01391-7

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Mutations in the common gamma chain (gamma c) of cytokine receptors account for human X-linked severe combined immunodeficiency disease, gamma c contributes to ligand binding and signaling as a component of five cytokine receptors: interleukin-2-receptor (IL-2R), IL-4R, IL-7R, IL-9R and IL-15R. Here, Thomas Malek and colleagues discuss the contribution of individual gamma c-dependent cytokines in both conventional and intraepithelial T-cell development.

引用

页码：71 / 76

页数：6

共 53 条

[1] Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice
Akashi, K
Kondo, M
vonFreedenJeffry, U
Murray, R
Weissman, IL
[J]. CELL, 1997, 89 (07) : 1033 - 1041
[2] IL-7 receptor and VDJ recombination: Trophic versus mechanistic actions
Candeias, S
Muegge, K
Durum, SK
[J]. IMMUNITY, 1997, 6 (05) : 501 - 508
[3] DEFECTIVE LYMPHOID DEVELOPMENT IN MICE LACKING EXPRESSION OF THE COMMON CYTOKINE RECEPTOR-GAMMA CHAIN
CAO, XQ
SHORES, EW
HULI, J
ANVER, MR
KELSALL, BL
RUSSELL, SM
DRAGO, J
NOGUCHI, M
GRINBERG, A
BLOOM, ET
PAUL, WE
KATZ, SI
LOVE, PE
LEONARD, WJ
[J]. IMMUNITY, 1995, 2 (03) : 223 - 238
[4] Identification of a novel developmental stage marking lineage commitment of progenitor thymocytes
Carlyle, JR
Michie, AM
Furlonger, C
Nakano, T
Lenardo, MJ
Paige, CJ
ZunigaPflucker, JC
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1997, 186 (02) : 173 - 182
[5] NONRANDOM X-CHROMOSOME INACTIVATION IN B-CELLS FROM CARRIERS OF X-CHROMOSOME-LINKED SEVERE COMBINED IMMUNODEFICIENCY
CONLEY, ME
LAVOIE, A
BRIGGS, C
BROWN, P
GUERRA, C
PUCK, JM
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (09) : 3090 - 3094
[6] Critical role for the common cytokine receptor gamma chain in intrathymic and peripheral T cell selection
DiSanto, JP
GuyGrand, D
Fisher, A
Tarakhovsky, A
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1996, 183 (03) : 1111 - 1118
[7] LYMPHOID DEVELOPMENT IN MICE WITH A TARGETED DELETION OF THE INTERLEUKIN-2 RECEPTOR-GAMMA CHAIN
DISANTO, JP
MULLER, W
GUYGRAND, D
FISCHER, A
RAJEWSKY, K
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (02) : 377 - 381
[8] Naturally occurring primary deficiencies of the immune system
Fischer, A
CavazzanaCalvo, M
DesaintBasile, G
DeVillartay, JP
DiSanto, JP
Hivroz, C
RieuxLaucat, F
LeDeist, F
[J]. ANNUAL REVIEW OF IMMUNOLOGY, 1997, 15 : 93 - 124
[9] GODFREY DI, 1993, J IMMUNOL, V150, P4244
[10] CONTROL POINTS IN EARLY T-CELL DEVELOPMENT
GODFREY, DI
ZLOTNIK, A
[J]. IMMUNOLOGY TODAY, 1993, 14 (11): : 547 - 553

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