Out of synch:: Clock mutation causes obesity in mice

被引：16

作者：

Williams, DL ^{[1
]}

Schwartz, MW

机构：

[1] Harborview Med Ctr, Dept Med, Seattle, WA 98104 USA

[2] Univ Washington, Seattle, WA 98104 USA

来源：

CELL METABOLISM | 2005年 / 1卷 / 06期

关键词：

D O I：

10.1016/j.cmet.2005.05.007

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The Clock gene encodes an essential component of the "master clock" driving circadian rhythm in the hypothalamic suprachiasmatic nucleus (SCN). New evidence that Clock mutant mice are hyperphagic and obese suggests a previously unrecognized link between molecular controls of circadian rhythm and energy homeostasis.

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收藏

页码：355 / 356

页数：2

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