The personality and quality of life in HNSCC patients following treatment

被引:40
作者
Aarstad, HJ [1 ]
Aarstad, AKH
Birkhaug, EJ
Bru, E
Olofsson, J
机构
[1] Haukeland Hosp, Dept Otolaryngol Head & Neck Surg, N-5021 Bergen, Norway
[2] Bergen Univ Coll, N-5008 Bergen, Norway
[3] Stavanger Univ Coll, N-4091 Stavanger, Norway
关键词
neoplasms; squamous carcinoma; quality of life; neuroticism; extraversion; radiation;
D O I
10.1016/S0959-8049(03)00308-3
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The aim of the present study was to investigate the association between self-reported quality of life (QoL) and personality in successfully treated primary head and neck squamous cell carcinoma (HNSCC) patients. We determined QoL using the European Organisation for Research and Treatment of Cancer Quality of life Questionnaire (EORTC-QLQ) C30/H&N35, and personality by the Eysenck Personality Inventory (EPI). All patients younger than 80 years who had been diagnosed with HNSCC in Western Norway in the period from 1992 to 1997, and who had survived until 1999, were sampled. 96 patients (a 90% response rate) were included. Questionnaires were also mailed to all Norwegian laryngectomised patients; 104 patients returned the questionnaires (a 50% response rate). The neuroticism scores were test re-test reliable as determined by the neuroticism scores measured at the primary HNSCC diagnosis for a sub-sample (N=22) of the included patients. High neuroticism was associated with a low QoL in both patient samples. The neuroticism score was associated with the QLQ-C30 scales (common variance: 17-25%) and all QoL scores in the laryngectomised group (common variance: 11-25%), and the H&N35 symptom scores in the laryngectomised sample. The associations could still be shown when adjustments were made for gender, age, marital status, educational level, number of children and level of treatment. Extraversion was associated with general QoL, physical and emotional scores in the HNSCC patient sample. Radiation therapy in the HNSCC sample was associated with the H&N35 symptom scores, but different ones to those associated with neuroticism. In conclusion, high neuroticism, but not extraversion, is associated with a lowered QoL. (C) 2003 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1852 / 1860
页数:9
相关论文
共 38 条
[11]   NEUROTICISM, SOMATIC COMPLAINTS, AND DISEASE - IS THE BARK WORSE THAN THE BITE [J].
COSTA, PT ;
MCCRAE, RR .
JOURNAL OF PERSONALITY, 1987, 55 (02) :299-316
[12]   INFLUENCE OF EXTRAVERSION AND NEUROTICISM ON SUBJECTIVE WELL-BEING - HAPPY AND UNHAPPY PEOPLE [J].
COSTA, PT ;
MCCRAE, RR .
JOURNAL OF PERSONALITY AND SOCIAL PSYCHOLOGY, 1980, 38 (04) :668-678
[13]   HYPOCHONDRIASIS, NEUROTICISM, AND AGING - WHEN ARE SOMATIC COMPLAINTS UNFOUNDED [J].
COSTA, PT ;
MCCRAE, RR .
AMERICAN PSYCHOLOGIST, 1985, 40 (01) :19-28
[14]   Quality of life evaluation in oncological clinical trials - the EORTC model [J].
de Haes, J ;
Curran, D ;
Young, T ;
Bottomley, A ;
Flechtner, H ;
Aaronson, N ;
Blazeby, J ;
Bjordal, K ;
Brandberg, Y ;
Greimel, E ;
Maher, J ;
Sprangers, M ;
Cull, A .
EUROPEAN JOURNAL OF CANCER, 2000, 36 (07) :821-825
[15]   Psycho-oncology: Where have we been? Where are we going? [J].
Dolbeault, S ;
Szporn, A ;
Holland, JC .
EUROPEAN JOURNAL OF CANCER, 1999, 35 (11) :1554-1558
[16]  
Eysenck H. J., 1985, Personality and individual differences: A natural science approach, DOI 13877
[17]  
Eysenck HJ, 1975, Manual of the eysenck personality questionnaire
[18]   First year after head and neck cancer: Quality of life [J].
Gritz, ER ;
Carmack, CL ;
de Moor, C ;
Coscarelli, A ;
Schacherer, CW ;
Meyers, EG ;
Abemayor, E .
JOURNAL OF CLINICAL ONCOLOGY, 1999, 17 (01) :352-360
[19]  
Hammerlid E, 1999, OTOLARYNG HEAD NECK, V120, P507
[20]   A prospective multicentre study in Sweden and Norway of mental distress and psychiatric morbidity in head and neck cancer patients [J].
Hammerlid, E ;
Ahlner-Elmqvist, M ;
Bjordal, K ;
Biörklund, A ;
Evensen, J ;
Boysen, M ;
Jannert, M ;
Kaasa, S ;
Sullivan, M ;
Westin, T .
BRITISH JOURNAL OF CANCER, 1999, 80 (5-6) :766-774