A short chemoenzymatic synthesis of (+)-narciclasine

被引:89
作者
Gonzalez, D [1 ]
Martinot, T [1 ]
Hudlicky, T [1 ]
机构
[1] Univ Florida, Dept Chem, Gainesville, FL 32611 USA
基金
美国国家科学基金会;
关键词
D O I
10.1016/S0040-4039(99)00433-5
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The title alkaloid has been synthesized in eight operations from dibromobenzene and o-vanillin, via enzymatic oxidation of the former compound, Suzuki coupling and a Bischler-Napieralski type cyclization as the key transformations. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:3077 / 3080
页数:4
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