Ensembl 2019

被引：678

作者：

Cunningham, Fiona ^{[1
]}

Achuthan, Premanand ^{[1
]}

Akanni, Wasiu ^{[1
]}

Allen, James ^{[1
]}

Amode, M. Ridwan ^{[1
]}

Armean, Irina M. ^{[1
]}

Bennett, Ruth ^{[1
]}

Bhai, Jyothish ^{[1
]}

Billis, Konstantinos ^{[1
]}

Boddu, Sanjay ^{[1
]}

Cummins, Carla ^{[1
]}

Davidson, Claire ^{[1
]}

Dodiya, Kamalkumar Jayantilal ^{[1
]}

Gall, Astrid ^{[1
]}

Giron, Carlos Garcia ^{[1
]}

Gil, Laurent ^{[1
]}

Grego, Tiago ^{[1
]}

Haggerty, Leanne ^{[1
]}

Haskell, Erin ^{[1
]}

Hourlier, Thibaut ^{[1
]}

Izuogu, Osagie G. ^{[1
]}

Janacek, Sophie H. ^{[1
]}

Juettemann, Thomas ^{[1
]}

Kay, Mike ^{[1
]}

Laird, Matthew R. ^{[1
]}

Lavidas, Ilias ^{[1
]}

Liu, Zhicheng ^{[1
]}

Loveland, Jane E. ^{[1
]}

Marugan, Jose C. ^{[1
]}

Maurel, Thomas ^{[1
]}

McMahon, Aoife C. ^{[1
]}

Moore, Benjamin ^{[1
]}

Morales, Joannella ^{[1
]}

Mudge, Jonathan M. ^{[1
]}

Nuhn, Michael ^{[1
]}

Ogeh, Denye ^{[1
]}

Parker, Anne ^{[1
]}

Parton, Andrew ^{[1
]}

Patricio, Mateus ^{[1
]}

Salam, Ahamed Imran Abdul ^{[1
]}

Schmitt, Bianca M. ^{[1
]}

Schuilenburg, Helen ^{[1
]}

Sheppard, Dan ^{[1
]}

Sparrow, Helen ^{[1
]}

Stapleton, Eloise ^{[1
]}

Szuba, Marek ^{[1
]}

Taylor, Kieron ^{[1
]}

Threadgold, Glen ^{[1
]}

Thormann, Anja ^{[1
]}

Vullo, Alessandro ^{[1
]}

机构：

[1] European Bioinformat Inst, European Mol Biol Lab, Wellcome Genome Campus, Cambridge CB10 1SD, England

来源：

NUCLEIC ACIDS RESEARCH | 2019年 / 47卷 / D1期

基金：

欧盟地平线“2020”; 美国国家卫生研究院; 英国生物技术与生命科学研究理事会; 英国惠康基金;

关键词：

GENOMES; PATHOGENICITY; ANNOTATIONS; BIOLOGY;

D O I：

10.1093/nar/gky1113

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

The Ensembl project (https://www.ensembl.org) makes key genomic data sets available to the entire scientific community without restrictions. Ensembl seeks to be a fundamental resource driving scientific progress by creating, maintaining and updating reference genome annotation and comparative genomics resources. This year we describe our new and expanded gene, variant and comparative annotation capabilities, which led to a 50% increase in the number of vertebrate genomes we support. We have also doubled the number of available human variants and added regulatory regions for many mouse cell types and developmental stages. Our data sets and tools are available via the Ensembl website as well as a through a RESTful webservice, Perl application programming interface and as data files for download.

引用

页码：D745 / D751

页数：7

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