Templating effect of lipid membranes on Alzheimer's amyloid beta peptide

被引：40

作者：

Ege, C

Majewski, J

Wu, GH

Kjaer, K

Lee, KYC ^{[1
]}

机构：

[1] Univ Chicago, James Franck Inst, Dept Chem, Chicago, IL 60637 USA

[2] Univ Chicago, Inst Biophys Dynam, Chicago, IL 60637 USA

[3] Los Alamos Natl Lab, Los Alamos Neutron Scattering Ctr, Los Alamos, NM 87545 USA

[4] Riso Natl Lab, Dept Mat Res, DK-4000 Roskilde, Denmark

来源：

CHEMPHYSCHEM | 2005年 / 6卷 / 02期

关键词：

Alzheimer's disease; monolayers; phospholipids; X-ray diffraction; X-ray reflectivity;

D O I：

10.1002/cphc.200400468

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Electrostatic influence on peptide association The first X-ray reflectivity and grazing-incidence X-ray diffraction study on amyloid beta peptide and lipid monolayers provides insight into the differences in the interaction of the peptide with cationic and anionic monolayers (see picture). A unique templating effect is observed in the latter case. © 2005 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

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收藏

页码：226 / 229

页数：4

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