Synthesis and properties of 3-acyl-γ-pyrones, a novel class of flavones and chromones

被引：64

作者：

Ganguly, AK ^{[1
]}

Kaur, S

Mahata, PK

Biswas, D

Pramanik, BN

Chan, TM

机构：

[1] Stevens Inst Technol, Hoboken, NJ 07030 USA

[2] Schering Plough Corp, Inst Res, Kenilworth, NJ 07033 USA

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 23期

关键词：

synthesis; heterocycles;

D O I：

10.1016/j.tetlet.2005.04.010

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Using modified Baker-Venkataraman reaction a novel class of 3-acyl flavones and chromones have been synthesised. Reaction mechanism for their formation have been elucidated. The properties of 3-acyl flavonoids indicate them to be precursors for the synthesis of flavones. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：4119 / 4121

页数：3

共 7 条

[1] Molecular rearrangement of some o-acyloxyacetophenones and the mechanism of the production of 3-acylchromones [J].

Baker, W .

JOURNAL OF THE CHEMICAL SOCIETY, 1933, :1381-1389

[2]

HIRAO I, 1984, SYNTHESIS-STUTTGART, P1076

[3] Cancer preventive effects of flavonoids - a review [J].

Le Marchand, L .

BIOMEDICINE & PHARMACOTHERAPY, 2002, 56 (06) :296-301

[4] Synthetical experiments in the chromone group Part XIV The action of sodamide on l-acyloxy-2-acetonaphthones [J].

Mahal, HS ;

Venkataraman, K .

JOURNAL OF THE CHEMICAL SOCIETY, 1934, :1767-1769

[5] Dietary bioflavonoids induce apoptosis in human leukemia cells [J].

Matsui, J ;

Kiyokawa, N ;

Takenouchi, H ;

Taguchi, T ;

Suzuki, K ;

Shiozawa, Y ;

Saito, M ;

Tang, WR ;

Katagiri, YU ;

Okita, H ;

Fujimoto, J .

LEUKEMIA RESEARCH, 2005, 29 (05) :573-581

[6]

Riva C, 1997, SYNTHESIS-STUTTGART, P195

[7] Cyclin-dependent kinases: Initial approaches to exploit a novel therapeutic target [J].

Sausville, EA ;

Zaharevitz, D ;

Gussio, R ;

Meijer, L ;

Louarn-Leost, M ;

Kunick, C ;

Schultz, R ;

Lahusen, T ;

Headlee, D ;

Stinson, S ;

Arbuck, SG ;

Senderowicz, A .

PHARMACOLOGY & THERAPEUTICS, 1999, 82 (2-3) :285-292

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