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Transcriptome analysis of the Vibrio fischeri LuxR-LuxI regulon
被引:59
作者:
Antunes, Luis Caetano M.
Schaefer, Amy L.
Ferreira, Rosana B. R.
Qin, Nan
Stevens, Ann M.
Ruby, Edward G.
Greenberg, E. Peter
机构:
[1] Univ Iowa, Dept Microbiol, Iowa City, IA 52242 USA
[2] Univ Washington, Dept Microbiol, Seattle, WA 98195 USA
[3] Virginia Tech, Dept Biol Sci, Blacksburg, VA 24061 USA
[4] Univ Wisconsin, Dept Med Microbiol & Immunol, Madison, WI 53706 USA
关键词:
D O I:
10.1128/JB.00736-07
中图分类号:
Q93 [微生物学];
学科分类号:
071005 ;
100705 ;
摘要:
The Vibrio fischeri quorum-sensing signal N-3-oxohexanoyl-L-homoserine lactone (30C6-HSL) activates expression of the seven-gene luminescence operon. We used microarrays to unveil 18 additional 30C6-HSL-controlled genes, 3 of which had been identified by other means previously. We show most of these genes are regulated by the 30C6-HSL-responsive transcriptional regulator LuxR directly. This demonstrates that V. fischeri quorum sensing regulates a substantial number of genes other than those involved in light production.
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页码:8387 / 8391
页数:5
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