Model systems for flavoenzyme activity. Control of flavin recognition via specific electrostatic interactions

被引：35

作者：

Goodman, AJ ^{[1
]}

Breinlinger, EC ^{[1
]}

McIntosh, CM ^{[1
]}

Grimaldi, LN ^{[1
]}

Rotello, VM ^{[1
]}

机构：

[1] Univ Massachusetts, Dept Chem, Amherst, MA 01003 USA

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 10期

关键词：

D O I：

10.1021/ol015838l

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A model system has been used to study the interactions of dipole containing aromatic systems with oxidized and reduced flavin, Ab initio computational and experimental studies show that dipole orientation within the host is a critical determinant for recognition and redox behavior of the flavin guest.

引用

页码：1531 / 1534

页数：4

共 31 条

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