FlyBase: integration and improvements to query tools

被引:114
作者
Wilson, Robert J. [1 ]
Goodman, Joshua L. [1 ]
Strelets, Victor B. [1 ]
机构
[1] Indiana Univ, Dept Biol, Bloomington, IN 47405 USA
基金
英国医学研究理事会;
关键词
D O I
10.1093/nar/gkm930
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
FlyBase (http://flybase.org) is the primary resource for molecular and genetic information on the Drosophilidae. The database serves researchers of diverse backgrounds and interests, and offers several different query tools to provide efficient access to the data available and facilitate the discovery of significant relationships within the database. Recently, FlyBase has developed Interactions Browser and enhanced GBrowse, which are graphical query tools, and made improvements to the search tools QuickSearch and QueryBuilder. Furthermore, these search tools have been integrated with Batch Download and new analysis tools through a more flexible search results list, providing powerful ways of exploring the data in FlyBase.
引用
收藏
页码:D588 / D593
页数:6
相关论文
共 7 条
[1]   Evolution of genes and genomes on the Drosophila phylogeny [J].
Clark, Andrew G. ;
Eisen, Michael B. ;
Smith, Douglas R. ;
Bergman, Casey M. ;
Oliver, Brian ;
Markow, Therese A. ;
Kaufman, Thomas C. ;
Kellis, Manolis ;
Gelbart, William ;
Iyer, Venky N. ;
Pollard, Daniel A. ;
Sackton, Timothy B. ;
Larracuente, Amanda M. ;
Singh, Nadia D. ;
Abad, Jose P. ;
Abt, Dawn N. ;
Adryan, Boris ;
Aguade, Montserrat ;
Akashi, Hiroshi ;
Anderson, Wyatt W. ;
Aquadro, Charles F. ;
Ardell, David H. ;
Arguello, Roman ;
Artieri, Carlo G. ;
Barbash, Daniel A. ;
Barker, Daniel ;
Barsanti, Paolo ;
Batterham, Phil ;
Batzoglou, Serafim ;
Begun, Dave ;
Bhutkar, Arjun ;
Blanco, Enrico ;
Bosak, Stephanie A. ;
Bradley, Robert K. ;
Brand, Adrianne D. ;
Brent, Michael R. ;
Brooks, Angela N. ;
Brown, Randall H. ;
Butlin, Roger K. ;
Caggese, Corrado ;
Calvi, Brian R. ;
de Carvalho, A. Bernardo ;
Caspi, Anat ;
Castrezana, Sergio ;
Celniker, Susan E. ;
Chang, Jean L. ;
Chapple, Charles ;
Chatterji, Sourav ;
Chinwalla, Asif ;
Civetta, Alberto .
NATURE, 2007, 450 (7167) :203-218
[2]   FlyBase: genomes by the dozen [J].
Crosby, Madeline A. ;
Goodman, Joshua L. ;
Strelets, Victor B. ;
Zhang, Peili ;
Gelbart, William M. .
NUCLEIC ACIDS RESEARCH, 2007, 35 :D486-D491
[3]   A Chado case study: an ontology-based modular schema for representing genome-associated biological information [J].
Mungall, Christopher J. ;
Emmert, David B. .
BIOINFORMATICS, 2007, 23 (13) :I337-I346
[4]   Discovery of functional elements in 12 Drosophila genomes using evolutionary signatures [J].
Stark, Alexander ;
Lin, Michael F. ;
Kheradpour, Pouya ;
Pedersen, Jakob S. ;
Parts, Leopold ;
Carlson, Joseph W. ;
Crosby, Madeline A. ;
Rasmussen, Matthew D. ;
Roy, Sushmita ;
Deoras, Ameya N. ;
Ruby, J. Graham ;
Brennecke, Julius ;
Hodges, Emily ;
Hinrichs, Angie S. ;
Caspi, Anat ;
Park, Seung-Won ;
Han, Mira V. ;
Maeder, Morgan L. ;
Polansky, Benjamin J. ;
Robson, Bryanne E. ;
Aerts, Stein ;
van Helden, Jacques ;
Hassan, Bassem ;
Gilbert, Donald G. ;
Eastman, Deborah A. ;
Rice, Michael ;
Weir, Michael ;
Hahn, Matthew W. ;
Park, Yongkyu ;
Dewey, Colin N. ;
Pachter, Lior ;
Kent, W. James ;
Haussler, David ;
Lai, Eric C. ;
Bartel, David P. ;
Hannon, Gregory J. ;
Kaufman, Thomas C. ;
Eisen, Michael B. ;
Clark, Andrew G. ;
Smith, Douglas ;
Celniker, Susan E. ;
Gelbart, William M. ;
Kellis, Manolis .
NATURE, 2007, 450 (7167) :219-232
[5]   The Generic Genome Browser: A building block for a model organism system database [J].
Stein, LD ;
Mungall, C ;
Shu, SQ ;
Caudy, M ;
Mangone, M ;
Day, A ;
Nickerson, E ;
Stajich, JE ;
Harris, TW ;
Arva, A ;
Lewis, S .
GENOME RESEARCH, 2002, 12 (10) :1599-1610
[6]  
STURTEVANT AH, 1965, HIST GENETICS, P45
[7]   Automated data integration for developmental biological research [J].
Zhong, Weiwei ;
Sternberg, Paul W. .
DEVELOPMENT, 2007, 134 (18) :3227-3238