Carbohydrate arrays as tools for research and diagnostics

被引：162

作者：

Horlacher, Tim ^{[1
]}

Seeberger, Peter H. ^{[1
]}

机构：

[1] ETH, Organ Chem Lab, CH-8093 Zurich, Switzerland

来源：

CHEMICAL SOCIETY REVIEWS | 2008年 / 37卷 / 07期

关键词：

D O I：

10.1039/b708016f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In a very short time, carbohydrate microarrays have become important tools to investigate binding events that involve sugars. High throughput analysis of carbohydrate interactions with a wide range of binding partners, including proteins, RNA, whole cells and viruses, can be performed. Questions ranging from simple binding events to in-depth kinetic analysis can be addressed. This tutorial review summarizes methods to produce carbohydrate microarrays as well as their use. Some selected examples illustrate applications and the potential that these tools hold.

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页码：1414 / 1422

页数：9

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