A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version)

被引：2539

作者：

Jin, Ying-Hui ^{[1
]}

Cai, Lin ^{[2
]}

Cheng, Zhen-Shun ^{[3
]}

Cheng, Hong ^{[4
]}

Deng, Tong ^{[1
,5
]}

Fan, Yi-Pin ^{[6
,7
]}

Fang, Cheng ^{[1
]}

Huang, Di ^{[1
]}

Huang, Lu-Qi ^{[6
,7
]}

Huang, Qiao ^{[1
]}

Han, Yong ^{[2
]}

Hu, Bo ^{[8
]}

Hu, Fen ^{[8
]}

Li, Bing-Hui ^{[1
,5
]}

Li, Yi-Rong ^{[9
]}

Liang, Ke ^{[10
]}

Lin, Li-Kai ^{[2
]}

Luo, Li-Sha ^{[1
]}

Ma, Jing ^{[8
]}

Ma, Lin-Lu ^{[1
]}

Peng, Zhi-Yong ^{[8
]}

Pan, Yun-Bao ^{[9
]}

Pan, Zhen-Yu ^{[11
]}

Ren, Xue-Qun ^{[5
]}

Sun, Hui-Min ^{[12
]}

Wang, Ying ^{[13
]}

Wang, Yun-Yun ^{[1
]}

Weng, Hong ^{[1
]}

Wei, Chao-Jie ^{[3
]}

Wu, Dong-Fang ^{[4
]}

Xia, Jian ^{[14
]}

Xiong, Yong ^{[10
]}

Xu, Hai-Bo ^{[15
]}

Yao, Xiao-Mei ^{[16
]}

Yuan, Yu-Feng ^{[2
]}

Ye, Tai-Sheng ^{[17
]}

Zhang, Xiao-Chun ^{[15
]}

Zhang, Ying-Wen ^{[17
]}

Zhang, Yin-Gao ^{[2
]}

Zhang, Hua-Min ^{[6
,7
]}

Zhao, Yan ^{[14
]}

Zhao, Ming-Juan ^{[1
]}

Zi, Hao ^{[1
,5
]}

Zeng, Xian-Tao ^{[1
,18
]}

Wang, Yong-Yan ^{[6
,7
]}

Wang, Xing-Huan ^{[1
,2
]}

机构：

[1] Wuhan Univ, Zhongnan Hosp, Ctr Evidence Based & Translat Med, Wuhan 430071, Peoples R China

[2] Wuhan Univ, Inst Hosp Management, Wuhan 430071, Peoples R China

[3] Wuhan Univ, Dept Resp Med, Zhongnan Hosp, Wuhan 430071, Peoples R China

[4] Wuhan Univ, Dept Pharm, Zhongnan Hosp, Wuhan 430071, Peoples R China

[5] Henan Univ, Inst Evidence Based Med & Knowledge Translat, Kaifeng 475000, Peoples R China

[6] China Acad Chinese Med Sci, Beijing 100700, Peoples R China

[7] China Ctr Evidence Based Tradit Chinese Med CCEBT, Beijing 100700, Peoples R China

[8] Wuhan Univ, Dept Crit Care Med, Zhongnan Hosp, Wuhan 430071, Peoples R China

[9] Wuhan Univ, Dept Clin Lab, Zhongnan Hosp, Wuhan 430071, Peoples R China

[10] Wuhan Univ, Dept Infect Dis, Zhongnan Hosp, Wuhan 430071, Peoples R China

[11] Wuhan Univ, Div Med Affairs, Zhongnan Hosp, Wuhan 430071, Peoples R China

[12] Wuhan Univ, Div Nursing Affairs, Zhongnan Hosp, Wuhan 430071, Peoples R China

[13] Wuhan Univ, Off Nosocomial Infect Control, Zhongnan Hosp, Wuhan 430071, Peoples R China

[14] Wuhan Univ, Emergency Ctr, Zhongnan Hosp, Wuhan 430071, Peoples R China

[15] Wuhan Univ, Dept Radiol, Zhongnan Hosp, Wuhan 430071, Peoples R China

[16] McMaster Univ, Dept Hlth Res Methods Evidence & Impact, Hamilton, ON L8S 4L8, Canada

[17] McMaster Univ, Dept Tradit Chinese Med, Zhongnan Hosp, Wuhan 430071, Peoples R China

[18] Wuhan Univ, Global Hlth Inst, Wuhan 430072, Peoples R China

来源：

MILITARY MEDICAL RESEARCH | 2020年 / 7卷 / 01期

基金：

新加坡国家研究基金会; 美国国家科学基金会; 俄罗斯科学基金会;

关键词：

2019 novel coronavirus; 2019-nCoV; Respiratory disease; Pneumonia; Infectious diseases; Rapid advice guideline; Clinical practice guideline; Evidence-based medicine; MERS; LOPINAVIR/RITONAVIR; RIBAVIRIN;

D O I：

10.1186/s40779-020-0233-6

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In December 2019, a new type viral pneumonia cases occurred in Wuhan, Hubei Province; and then named "2019 novel coronavirus (2019-nCoV)" by the World Health Organization (WHO) on 12 January 2020. For it is a never been experienced respiratory disease before and with infection ability widely and quickly, it attracted the world's attention but without treatment and control manual. For the request from frontline clinicians and public health professionals of 2019-nCoV infected pneumonia management, an evidence-based guideline urgently needs to be developed. Therefore, we drafted this guideline according to the rapid advice guidelines methodology and general rules of WHO guideline development; we also added the first-hand management data of Zhongnan Hospital of Wuhan University. This guideline includes the guideline methodology, epidemiological characteristics, disease screening and population prevention, diagnosis, treatment and control (including traditional Chinese Medicine), nosocomial infection prevention and control, and disease nursing of the 2019-nCoV. Moreover, we also provide a whole process of a successful treatment case of the severe 2019-nCoV infected pneumonia and experience and lessons of hospital rescue for 2019-nCoV infections. This rapid advice guideline is suitable for the first frontline doctors and nurses, managers of hospitals and healthcare sections, community residents, public health persons, relevant researchers, and all person who are interested in the 2019-nCoV.

引用

页数：23

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