SCANMOT: searching for similar sequences using a simultaneous scan of multiple sequence motifs

被引:10
作者
Chakrabarti, S
Anand, AP
Bhardwaj, N
Pugalenthi, G
Sowdhamini, R [1 ]
机构
[1] Natl Ctr Biol Sci, Bangalore 560065, Karnataka, India
[2] MSIT, Int Inst Informat Technol, Hyderabad 500019, Andhra Pradesh, India
[3] Indian Inst Technol, Dept Chem Engn, Bombay 400076, Maharashtra, India
基金
英国惠康基金;
关键词
D O I
10.1093/nar/gki493
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Establishment of similarities between proteins is very important for the study of the relationship between sequence, structure and function and for the analysis of evolutionary relationships. Motif-based search methods play a crucial role in establishing the connections between proteins that are particularly useful for distant relationships. This paper reports SCANMOT, a web-based server that searches for similarities between proteins by simultaneous matching of multiple motifs. SCANMOT searches for similar sequences in entire sequence databases using multiple conserved regions and utilizes inter-motif spacing as restraints. The SCANMOT server is available via http:// www.ncbs.res.in/similar to faculty/mini/scanmot/scanmot.html.
引用
收藏
页码:W274 / W276
页数:3
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