A general method for the Suzuki-Miyaura cross-coupling of sterically hindered aryl chlorides: Synthesis of di- and tri-ortho-substituted biaryls in 2-propanol at room temperature

被引:534
作者
Navarro, O [1 ]
Kelly, RA [1 ]
Nolan, SP [1 ]
机构
[1] Univ New Orleans, Dept Chem, New Orleans, LA 70148 USA
关键词
D O I
10.1021/ja038631r
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The catalytic formation of di- and trisubstituted ortho biaryl junctions has been achieved using a palladacylce pre-catalyst bearing a N-heterocyclic carbene ligand. This transformation is performed at room temperature in technical grade 2-propanol. Copyright © 2003 American Chemical Society.
引用
收藏
页码:16194 / 16195
页数:2
相关论文
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