RNA interference and heterochromatin in the fission yeast Schizosaccharomyces pombe

被引：110

作者：

Martienssen, RA ^{[1
]}

Zaratiegui, M ^{[1
]}

Goto, DB ^{[1
]}

机构：

[1] Cold Spring Harbor Lab, Cold Spring Harbor, NY 11724 USA

来源：

TRENDS IN GENETICS | 2005年 / 21卷 / 08期

关键词：

D O I：

10.1016/j.tig.2005.06.005

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Fission yeast is a useful model for RNA interference because it has single-copy genes for components of the RNAi pathway such as argonaute, dicer and RNA-dependent RNA polymerase (RdRP). Functions for RNAi revealed in S. pombe, such as heterochromatic silencing and chromosome segregation, are likely to be ancient because they are shared with some other eukaryotes. The underlying mechanisms are being rapidly unraveled.

引用

页码：450 / 456

页数：7

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