Building better vasculature

[41] The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis [J]. NATURE, 1999, 399 (6733) : 271 - 275

[42] Vascular endothelial growth factor (VEGF) and its receptors [J]. FASEB JOURNAL, 1999, 13 (01) : 9 - 22

[43] Oxygen-regulated and transactivating domains in endothelial PAS protein 1:: Comparison with hypoxia-inducible factor-1α [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (04) : 2060 - 2071

[44] Ubiquitination of hypoxia-inducible factor requires direct binding to the β-domain of the von Hippel-Lindau protein [J]. NATURE CELL BIOLOGY, 2000, 2 (07) : 423 - 427

[45] VASCULAR ENDOTHELIAL GROWTH-FACTOR (VEGF) INDUCES PLASMINOGEN ACTIVATORS AND PLASMINOGEN-ACTIVATOR INHIBITOR-1 IN MICROVASCULAR ENDOTHELIAL-CELLS [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1991, 181 (02) : 902 - 906

[46] Pugh CW, 1997, J BIOL CHEM, V272, P11205

[47] HIF-1α is required for solid tumor formation and embryonic vascularization [J]. EMBO JOURNAL, 1998, 17 (11) : 3005 - 3015

[48] Hypoxia-inducible factor 1 alpha (HIF-1 alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions - Its stabilization by hypoxia depends on redox-induced changes [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (36) : 22642 - 22647

[49] Semenza GL, 2000, GENE DEV, V14, P1983

[50] Regulation of mammalian O2 homeostasis by hypoxia- inducible factor 1 [J]. ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, 1999, 15 : 551 - 578

[41] The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis [J]. NATURE, 1999, 399 (6733) : 271 - 275

[42] Vascular endothelial growth factor (VEGF) and its receptors [J]. FASEB JOURNAL, 1999, 13 (01) : 9 - 22

[43] Oxygen-regulated and transactivating domains in endothelial PAS protein 1:: Comparison with hypoxia-inducible factor-1α [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (04) : 2060 - 2071

[44] Ubiquitination of hypoxia-inducible factor requires direct binding to the β-domain of the von Hippel-Lindau protein [J]. NATURE CELL BIOLOGY, 2000, 2 (07) : 423 - 427

[45] VASCULAR ENDOTHELIAL GROWTH-FACTOR (VEGF) INDUCES PLASMINOGEN ACTIVATORS AND PLASMINOGEN-ACTIVATOR INHIBITOR-1 IN MICROVASCULAR ENDOTHELIAL-CELLS [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1991, 181 (02) : 902 - 906

[46] Pugh CW, 1997, J BIOL CHEM, V272, P11205

[47] HIF-1α is required for solid tumor formation and embryonic vascularization [J]. EMBO JOURNAL, 1998, 17 (11) : 3005 - 3015

[48] Hypoxia-inducible factor 1 alpha (HIF-1 alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions - Its stabilization by hypoxia depends on redox-induced changes [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (36) : 22642 - 22647

[49] Semenza GL, 2000, GENE DEV, V14, P1983

[50] Regulation of mammalian O2 homeostasis by hypoxia- inducible factor 1 [J]. ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, 1999, 15 : 551 - 578