WebACT - an online companion for the artemis comparison tool

被引：72

作者：

Abbott, JC ^{[1
]}

Aanensen, DM

Rutherford, K

Butcher, S

Spratt, BG

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Ctr Bioinformat, Div Mol Biosci, London SW7 2AZ, England

[2] Sanger Inst, Pathogen Sequencing Unit, Cambridge CB10 1SA, England

[3] Univ London Imperial Coll Sci Technol & Med, Dept Infect Dis Epidemiol, London W2 1PG, England

来源：

BIOINFORMATICS | 2005年 / 21卷 / 18期

基金：

英国惠康基金;

关键词：

D O I：

10.1093/bioinformatics/bti601

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

WebACT is an online resource which enables the rapid provision of simultaneous BLAST comparisons between up to five genomic sequences in a format amenable for visualization with the well-known Artemis Comparison Tool (ACT). Comparisons can be generated on-the-fly using sequences directly retrieved via EMBL database queries, or by entering or uploading user sequences. Furthermore, pre-computed comparisons are available between all publicly available, completed prokaryotic genomes and plasmids currently contained within the Genome Reviews database (372 sequences, representing 175 different species). The system is designed to minimize the volume of downloaded data and maximize performance. Genome sequences, annotation and pre-computed comparisons are stored in a relational database allowing flexible querying based on user-defined sequence regions, from whole genome to a defined region flanking a specified gene. Comparison and sequence files, whether computed online or retrieved from the database of pre-computed genome comparisons, can be viewed online using ACT and are available for download.

引用

页码：3665 / 3666

页数：2

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