Functional characterization of KIHEM13, a hypoxic gene of Kluyveromyces lactis

被引：12

作者：

Blanco, M ^{[1
]}

Becerra, M ^{[1
]}

González-Siso, MI ^{[1
]}

Cerdán, ME ^{[1
]}

机构：

[1] Univ A Coruna, Dept Biol Celular & Mol, F Ciencias, La Coruna 15071, Spain

来源：

CANADIAN JOURNAL OF MICROBIOLOGY | 2005年 / 51卷 / 03期

关键词：

coproporphyrinogen oxidase (CPO); HEM13; hypoxic genes; Kluyveromyces lactis;

D O I：

10.1139/W04-133

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The KIHEM13 gene of Kluyveromyces lactis encoding the coproporphyrinogen oxidase (EC 1.3.3.3), an oxygen-requiring enzyme that catalyzes the sixth step of heme biosynthesis, was cloned and functionally characterized. The coding and upstream regions of KIHEM13 were analyzed and the putative cis regulatory elements were discussed in relation to the mechanisms of regulation of this hypoxic gene in K. lactis.

引用

页码：241 / 249

页数：9

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