Low serum cholesterol in suicide attempters

被引：121

作者：

Kunugi, H ^{[1
]}

Takei, N ^{[1
]}

Aoki, H ^{[1
]}

Nanko, S ^{[1
]}

机构：

[1] INST PSYCHIAT,DEPT MED PSYCHOL,GENET SECT,LONDON,ENGLAND

来源：

BIOLOGICAL PSYCHIATRY | 1997年 / 41卷 / 02期

关键词：

attempted suicide; cholesterol; depressive disorder; psychiatric diagnosis;

D O I：

10.1016/S0006-3223(95)00672-9

中图分类号：

Q189 [神经科学];

学科分类号：

071006 [神经生物学];

摘要：

Previous studies have shown an association between low serum cholesterol concentration and suicide; however, conflicting results have also been reported. To examine this potential association, cholesterol levels in 99 patients admitted to an emergency ward following an attempted suicide were compared with those in 74 nonsuicidal psychiatric inpatients, and those in 39 psychiatrically normal individuals with accidental injuries, Cholesterol concentrations in suicide attempters were found to be significantly lower compared with both psychiatric and normal controls, when sex, age, psychiatric diagnosis, and physical conditions (serum total protein and red blood cell count) were adjusted for. This significant relationship was observed in mood disorders and personality or neurotic disorders, but nor in schizophrenia spectrum disorders. These results support the previous claim that lower cholesterol level is associated with an increased risk of suicidal behavior. (C) 1997 Society of Biological Psychiatry

引用

页码：196 / 200

页数：5

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