Why minocycline is helpful in Huntington's disease

被引:16
作者
Bonelli, RM [1 ]
Kapfhammer, HP [1 ]
机构
[1] Karl Franzens Univ Graz, Univ Clin Psychiat, A-8036 Graz, Austria
关键词
D O I
10.1177/0269881103174008
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
引用
收藏
页码:461 / 461
页数:1
相关论文
共 11 条
[1]   Minocycline for the treatment of rheumatoid arthritis [J].
Alarcon, GS .
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA, 1998, 24 (03) :489-+
[2]   Minocycline slows progress of Huntington's disease in mice [J].
Berger, A .
BRITISH MEDICAL JOURNAL, 2000, 321 (7253) :70-70
[3]   Minocycline for Huntington's disease: An open label study [J].
Bonelli, RM ;
Heuberger, C ;
Reisecker, F .
NEUROLOGY, 2003, 60 (05) :883-884
[4]   Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease [J].
Chen, M ;
Ona, VO ;
Li, MW ;
Ferrante, RJ ;
Fink, KB ;
Zhu, S ;
Bian, J ;
Guo, L ;
Farrell, LA ;
Hersch, SM ;
Hobbs, W ;
Vonsattel, JP ;
Cha, JHJ ;
Friedlander, RM .
NATURE MEDICINE, 2000, 6 (07) :797-+
[5]   Maintained improvement with minocycline of a patient with advanced Huntington's disease [J].
Denovan-Wright, EM ;
Devarajan, S ;
Dursun, SM ;
Robertson, HA .
JOURNAL OF PSYCHOPHARMACOLOGY, 2002, 16 (04) :393-394
[6]   Benefits and risks of minocycline in rheumatoid arthritis [J].
Langevitz, P ;
Livneh, A ;
Bank, I ;
Pras, M .
DRUG SAFETY, 2000, 22 (05) :405-414
[7]   Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease [J].
Ona, VO ;
Li, MW ;
Vonsattel, JPG ;
Andrews, LJ ;
Khan, SQ ;
Chung, WM ;
Frey, AS ;
Menon, AS ;
Li, XJ ;
Stieg, PE ;
Yuan, JY ;
Penney, JB ;
Young, AB ;
Cha, JHJ ;
Friedlander, RM .
NATURE, 1999, 399 (6733) :263-267
[8]   Oral and systemic effects of prolonged minocycline therapy [J].
Patel, K ;
Cheshire, D ;
Vance, A .
BRITISH DENTAL JOURNAL, 1998, 185 (11-12) :560-562
[9]   Minocycline provides neuroprotection against N-methyl-D-aspartate neurotoxicity by inhibiting microglia [J].
Tikka, TM ;
Koistinaho, JE .
JOURNAL OF IMMUNOLOGY, 2001, 166 (12) :7527-7533
[10]   Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease [J].
Yamamoto, A ;
Lucas, JJ ;
Hen, R .
CELL, 2000, 101 (01) :57-66