Macrophage polarization comes of age

被引：980

作者：

Mantovani, A ^{[1
]}

Sica, A

Locati, M

机构：

[1] Ist Clin Humanitas, Milan, Italy

[2] Univ Milan, Inst Gen Pathol, Milan, Italy

来源：

IMMUNITY | 2005年 / 23卷 / 04期

关键词：

D O I：

10.1016/j.immuni.2005.10.001

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Functional polarization of macrophages into M1 or M2 cells is an operationally useful, simplified conceptual framework describing the plasticity of mononuclear phagocytes. Genetic approaches have begun to shed new light on mechanisms underlying macrophage polarization and on the actual in vivo significance of polarized M2 cells (Rauh et al., 2005 [this issue of Immunity]).

引用

页码：344 / 346

页数：3

共 13 条

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